We explored the effects of resilience in the healthcare setting during the COVID-19 pandemic in Germany. Our study sheds light on the cross-level effects of resilience in hospitals and thus responds to calls to research this empirically. In a cross-sectional study design, the perceptions of resilience of employees in hospitals and of transformations at the individual, team, and organizational level were analyzed. An online survey was conducted in summer 2020 in Germany in which 1,710 healthcare workers completed a self-report questionnaire. (...) Results indicate that resilience is both a highly interrelated construct on the individual and organizational level and also positively linked to perceptions of transformation as an indicator for demonstration of resilience. We also found a partial mediation effect of organizational resilience and team efficacy, respectively, on the relationship between individual resilience and perceived transformation on the individual and organizational level as well as a full mediation on the team level. The study highlights the interdependence of individual and organizational resilience and its impact on perceived transformation in German hospitals during the COVID-19 pandemic. Whereas team efficacy is crucial for performance in regular work operations, during a pandemic the organizational level becomes more relevant. Theoretical and practical implications are discussed. (shrink)

The ability to process center‐embedded structures has been claimed to represent a core function of the language faculty. Recently, several studies have investigated the learning of center‐embedded dependencies in artificial grammar settings. Yet some of the results seem to question the learnability of these structures in artificial grammar tasks. Here, we tested under which exposure conditions learning of center‐embedded structures in an artificial grammar is possible. We used naturally spoken syllable sequences and varied the presence of prosodic cues. The results (...) suggest that mere distributional information does not suffice for successful learning. Prosodic cues marking the boundaries of the major relevant units, however, can lead to learning success. Thus, our data are consistent with the hypothesis that center‐embedded syntactic structures can be learned in artificial grammar tasks if language‐like acoustic cues are provided. (shrink)

Objective: Atypical patterns of language lateralization due to early reorganizational processes constitute a challenge in the pre-surgical evaluation of patients with pharmaco-resistant epilepsy. There is no consensus on an optimal analysis method used for the identification of language dominance in MEG. This study examines the concordance between MEG source localization of beta power desynchronization and fMRI with regard to lateralization and localization of expressive and receptive language areas using a visual verb generation task.Methods: Twenty-five patients with pharmaco-resistant epilepsy, including six (...) patients with atypical language lateralization, and ten right-handed controls obtained MEG and fMRI language assessment. Fourteen patients additionally underwent the Wada test. We analyzed MEG beta power desynchronization in sensor (controls) and source space (patients and controls). Beta power decrease between 13 and 35 Hz was localized applying Dynamic Imaging of Coherent Sources Beamformer technique. Statistical inferences were grounded on cluster-based permutation testing for single subjects.Results: Event-related desynchronization of beta power in MEG was seen within the language-dominant frontal and temporal lobe and within the premotor cortex. Our analysis pipeline consistently yielded left language dominance with high laterality indices in controls. Language lateralization in MEG and Wada test agreed in all 14 patients for inferior frontal, temporal and pari... (shrink)

Progressive supranuclear palsy is a movement disorder with prominent tau neuropathology. Brain diseases with abnormal tau deposits are called tauopathies, the most common of which is Alzheimer's disease. Environmental causes of tauopathies include repetitive head trauma associated with some sports. To identify common genetic variation contributing to risk for tauopathies, we carried out a genome-wide association study of 1,114 individuals with PSP and 3,247 controls followed by a second stage in which we genotyped 1,051 cases and 3,560 controls for the (...) stage 1 SNPs that yielded P ≤ 10-3. We found significant previously unidentified signals associated with PSP risk at STX6, EIF2AK3 and MOBP. We confirmed two independent variants in MAPT affecting risk for PSP, one of which influences MAPT brain expression. The genes implicated encode proteins for vesicle-membrane fusion at the Golgi-endosomal interface, for the endoplasmic reticulum unfolded protein response and for a myelin structural component. © 2011 Nature America, Inc. All rights reserved. (shrink)

Students’ educational engagement is both an important predictor of study success and a key preventive factor for dropout. Vocational tracks in secondary education show high dropout rates. There is strong evidence that the solution to educational disengagement lies in student‐centred, powerful learning environments. This study investigates characteristics of PLEs from the perspective of students in vocational secondary education. Students’ perspectives on a learning environment are crucial for their satisfaction and learning engagement. Therefore, we investigated whether the perceived learning environment meets (...) the requirements of PLEs, and to what extent it meets students’ preferences. Additionally, it was investigated whether students who perceive their learning environment as more powerful, are also more engaged for school. Survey data of 532 students showed that student perceptions of their current learning environment were largely discrepant from the characteristics of PLEs. Students strongly asked for more challenging learning pathways, in combination with adaptive learning support. Students who perceived the characteristics of PLEs as being present, reported higher satisfaction and stronger engagement than students who perceived their education to be a less powerful environment. There is a need to redesign curricula in vocational education in such a way that these more intensely implement characteristics of PLEs. (shrink)

BackgroundStory recall tests have shown variable sensitivity to rate of cognitive decline in individuals with Alzheimer’s disease biomarkers. Although SR tasks are typically scored by obtaining a sum of items recalled, item-level analyses may provide additional sensitivity to change and AD processes. Here, we examined the difficulty and discrimination indices of each item from the Logical Memory SR task, and determined if these metrics differed by recall conditions, story version, lexical categories, serial position, and amyloid status.Methodsn = 1,141 participants from (...) the Wisconsin Registry for Alzheimer’s Prevention longitudinal study who had item-level data were included in these analyses, as well as a subset of n = 338 who also had amyloid positron emission tomography imaging. LM data were categorized into four lexical categories, and by serial position. We calculated difficulty and discriminability/memorability by item, category, and serial position and ran separate repeated measures ANOVAs for each recall condition, lexical category, and serial position. For the subset with amyloid imaging, we used a two-sample t-test to examine whether amyloid positive and amyloid negative groups differed in difficulty or discrimination for the same summary metrics.ResultsIn the larger sample, items were more difficult in the delayed recall condition across both story A and story B. Item discrimination was higher at delayed than immediate recall, and proper names had better discrimination than any of the other lexical categories or serial position groups. In the subsample with amyloid PET imaging, proper names were more difficult for Aβ+ than Aβ−; items in the verb and “other” lexical categories and all serial positions from delayed recall were more discriminate for the Aβ+ group compared to the Aβ− group.ConclusionThis study provides empirical evidence that both LM stories are effective at discriminating ability levels and amyloid status, and that individual items vary in difficulty and discrimination by amyloid status, while total scores do not. These results can be informative for the future development of sensitive tasks or composite scores for early detection of cognitive decline. (shrink)

One problem of interpreting research on subconscious processing is the possibility that participants are weakly conscious of the stimuli. Here, we compared the fMRI BOLD response in healthy adults to clearly visible single letters with the response to letters presented in the absence of any behavioural evidence of visibility . No letter catch trials served as a control condition. Forced-choice responses did not differ from chance when letter-to-background contrast was low, whereas they were almost 100% correct when contrast was high. (...) A comparison of fMRI BOLD signals for supraliminal and subliminal letters with the control trials revealed a signal increase in left BA 37 . Comparison of supraliminal with subliminal letters showed a significant increase in the right inferior frontal gyrus . Finally, a comparison of subliminal with supraliminal letters showed increases in the left middle temporal gyrus and the right extrastriate cortex. (shrink)

ABSTRACT This paper is intended to stimulate debate amongst stakeholders in the international research community on the topic of returning individual genetic research results to study participants. Pharmacogenetics and disease genetics studies are becoming increasingly prevalent, leading to a growing body of information on genetic associations for drug responsiveness and disease susceptibility with the potential to improve health care. Much of these data are presently characterized as exploratory (non‐validated or hypothesis‐generating). There is, however, a trend for research participants to be (...) permitted access to their personal data if they so choose. Researchers, sponsors, patient advocacy groups, ethics committees and regulatory authorities are consequently confronting the issue of whether, and how, study participants might receive their individual results. Noted international ethico‐legal guidelines and public policy positions in Europe and the United States are reviewed for background. The authors offer ‘Points‐to‐Consider’ regarding returning research results in the context of drug development trials based on their knowledge and experience. These considerations include: the clinical relevance of data, laboratory qualifications, informed consent procedures, confidentiality of medical information and the competency of persons providing results to participants. The discussion is framed as a benefit‐to‐risk assessment to balance the potential positive versus negative consequences to participants, while maintaining the integrity and feasibility of conducting genetic research studies. (shrink)

ABSTRACT Despite Institutional Review Board concerns about psychological harm arising from research participation, evidence from trauma-questionnaire research suggests that participation is typically well-tolerated by participants. Yet, it is unclear how participant experiences of in-lab trauma simulations align with IRB ethical guidelines. Thus, we compared reactions to a trauma film paradigm with reactions to a positive film task or cognitive tasks. Overall, relative to other conditions, the trauma film was well-tolerated by participants: they generally reported low-to-moderate negative emotions, moderate benefits, and (...) that participation was not worse than everyday stressors. Our results have implications for the research community in designing trauma-based research. (shrink)

If stem cell-based therapies are developed, we will likely confront a difficult problem of justice: for biological reasons alone, the new therapies might benefit only a limited range of patients. In fact, they might benefit primarily white Americans, thereby exacerbating long-standing differences in health and health care.

A partir de l’étude de corpus de textes, manuelle et informatique, nous présentons une réflexion sur l’analyse de texte ou de discours à travers l’exemple de l’exposition didactique. Celle-ci peut s’envisager à différents grains. Nous posons la question de la taille du texte, de son style collectif à travers sa disposition et ses marques. Nous interrogeons la pertinence du modèle choisi en relation avec la notion d’échelle. Enfin, nous posons la question de la résolution adéquate pour des logiciels d’analyse, à (...) l’aide d’une dizaine d’exemples. (shrink)

A partir de l’étude de corpus de textes, manuelle et informatique, nous présentons une réflexion sur l’analyse de texte ou de discours à travers l’exemple de l’exposition didactique. Celle-ci peut s’envisager à différents grains. Nous posons la question de la taille du texte, de son style collectif à travers sa disposition et ses marques. Nous interrogeons la pertinence du modèle choisi en relation avec la notion d’échelle. Enfin, nous posons la question de la résolution adéquate pour des logiciels d’analyse, à (...) l’aide d’une dizaine d’exemples. (shrink)

La philosophie de Baudrillard est inédite puisqu'il possède une façon originale de voir le monde, ses yeux étant ceux d'un philosophe-critique, d'un sociologue, d'un journaliste et d'un pataphysicien. Ce faisant, il possède une manière fort intéressante de nommer les faits. D'où toute la série de termes qu'il revisite ou invente surtout ceux formés par le préfixe hyper comme hyperconsommation, hypermarché, hyperréel, hypercorps, hyperespace et bien d'autres. Malgré sa quête du sens et du réel, Baudrillard débouche sur le non-sens et proclame (...) moyennement l'absence du réel. C'est comme si tout l'objectif de sa quête était uniquement la description du réel disparu et non la recherche et l'instauration du réel voire d'un nouveau réel. La recherche conduite ici s'attaque à la pensée hyperréelle de Jean Baudrillard tout en présentant l'originalité de cette pensée singulière et controversée. (shrink)

The aim of this paper is to contribute to debate on Hegel's conception of the relationship between religion and philosophy by proposing that it can be a read as a division of labour between Christian religion and speculative philosophy. This reading allows us to understand better Hegel's idea that religion and philosophy have the same content in two different forms. I distinguish between the institutional and the intrapersonal dimensions of Hegel's claim of a division of labour between religion and philosophy. (...) I then turn to a critique of Hegel's philosophy of religion by showing how David Friedrich Strauss's concluding dissertation from The Life of Jesus, Critically Examined can call our attention to some internal tensions within Hegel's conception. Although Strauss's interpretation does not present an insurmountable objection against Hegel's conception of a division of labour, it can help to illuminate to what extent Hegel oversimplified the practical implications that his conception might have for the priest's attempt to continue his instruction to the members of his community. (shrink)

Pancreatitis is a complex, progressively destructive inflammatory disorder. Alcohol was long thought to be the primary causative agent, but genetic contributions have been of interest since the discovery that rare PRSS1, CFTR and SPINK1 variants were associated with pancreatitis risk. We now report two associations at genome-wide significance identified and replicated at PRSS1-PRSS2 and X-linked CLDN2 through a two-stage genome-wide study. The PRSS1 variant likely affects disease susceptibility by altering expression of the primary trypsinogen gene. The CLDN2 risk allele is (...) associated with atypical localization of claudin-2 in pancreatic acinar cells. The homozygous CLDN2 genotype confers the greatest risk, and its alleles interact with alcohol consumption to amplify risk. These results could partially explain the high frequency of alcohol-related pancreatitis in men. © 2012 Nature America, Inc. All rights reserved. (shrink)

Cet important ouvrage de l’historienne Sasha Turner porte sur la période de 1780 à 1834 à la Jamaïque, période pendant laquelle la perspective de l’abolition de la traite (qui interviendra en 1807), puis de l’esclavage lui-même, conduisit, là comme ailleurs, les différents acteurs du système esclavagiste à réviser la politique jusqu’alors menée en matière de reproduction de la main d’œuvre et à adopter, bon gré mal gré, une politique nataliste. La connaissance des conditions de vie des femmes...

Résumé Cet article rend compte d’une recherche sur le vécu des couples confrontés au cancer. La qualité de vie du patient et de son entourage devient de plus en plus cruciale au fur et à mesure que s’accroît l’espérance de vie des personnes atteintes. Le couple constitue une entité psychique spécifique qui résulte de la dynamique intersubjective entre conjoints. Cette entité peut être atteinte en cas de maladie grave. L’étude servant d’appui à cet article porte sur l’annonce de la maladie, (...) la période des traitements et la rémission. Il est ainsi mis en évidence que le « syndrome de Lazare » ne concerne pas que la personne malade, mais également le conjoint et que l’homéostasie du couple est perturbée bien au-delà de l’annonce de la rémission. (shrink)

Résumé Cet article rend compte d’une recherche sur le vécu des couples confrontés au cancer. La qualité de vie du patient et de son entourage devient de plus en plus cruciale au fur et à mesure que s’accroît l’espérance de vie des personnes atteintes. Le couple constitue une entité psychique spécifique qui résulte de la dynamique intersubjective entre conjoints. Cette entité peut être atteinte en cas de maladie grave. L’étude servant d’appui à cet article porte sur l’annonce de la maladie, (...) la période des traitements et la rémission. Il est ainsi mis en évidence que le « syndrome de Lazare » ne concerne pas que la personne malade, mais également le conjoint et que l’homéostasie du couple est perturbée bien au-delà de l’annonce de la rémission. (shrink)

La cohabitation avec la dialyse à domicile, ce lieu privé habituellement préservé de la maladie, invite à des questionnements sur la dynamique du couple au regard du nouveau rôle de soignant endossé par le conjoint et de celui de patient assigné au conjoint malade. Les auteurs, psychologues cliniciennes, interrogent ici les motivations conscientes et inconscientes qui conduisent à cette décision commune et leurs retentissements sur la dynamique du couple. Différentes configurations relationnelles observées dans notre clinique seront abordées. L’article, cas clinique (...) à l’appui, montre l’intérêt d’un groupe thérapeutique avec malades et conjoints pour mettre à jour les enjeux, au niveau de la relation de couple, d’une prise en charge à domicile. (shrink)

This paper revisits the dynamic discussion about journalism’s role in representing and amplifying disability arts at the 2019 Cripping the Arts Symposium. Chronicling the dialogue of the “Representation” panel which included artists, arts and culture critics, journalists, and scholars, it reveals how arts and culture coverage contributes to the cultivation of disability, D/deaf, and mad art. Given that the relationship between journalism and disability communities continues to be fractured in Canada, speakers were invited to reflect on journalism and disability arts (...) in relation to their own engagement with media as subjects, authors, and critics of disability arts reviews. The methods for presentation were cripped in multiple ways to provide the fullest access possible. The panel concluded with examples of ableist fault lines in representation practices where the disabled figure is an absent “ghost” in journalistic representation, warnings against journalistic reliance on traditional and objective narratives, and a call for artists to claim and write their own stories. Ultimately, disabled, D/deaf, and mad artists need both control over artistic endeavours and output and influence over representation. This article reconnects journalism and disability communities, ultimately demonstrating that representation is a critical, co-constitutive process that can become more aesthetically and politically oriented toward social justice in its focus on disability, D/deaf, and mad arts. (shrink)

La cohabitation avec la dialyse à domicile, ce lieu privé habituellement préservé de la maladie, invite à des questionnements sur la dynamique du couple au regard du nouveau rôle de soignant endossé par le conjoint et de celui de patient assigné au conjoint malade. Les auteurs, psychologues cliniciennes, interrogent ici les motivations conscientes et inconscientes qui conduisent à cette décision commune et leurs retentissements sur la dynamique du couple. Différentes configurations relationnelles observées dans notre clinique seront abordées. L’article, cas clinique (...) à l’appui, montre l’intérêt d’un groupe thérapeutique avec malades et conjoints pour mettre à jour les enjeux, au niveau de la relation de couple, d’une prise en charge à domicile. (shrink)

L’analyse des réseaux sociaux est menée dans le domaine des sciences sociales depuis les années 1930. Le premier enjeu pour réaliser ces analyses se situe dans la collecte de l’information sur la structure de ces réseaux et sur leurs activités. Avec l’avènement du Web 2.0 et des technologies du Web sémantique, plusieurs mécanismes de collecte d’information sont désormais envisageables. Cependant, très peu d’utilisateurs sont conscients des facilités d’atteinte et de manipulation de leurs traces d’activités et de leurs données personnelles de (...) plus en plus rendus publics sur les réseaux socionumériques en particulier. Dans cet article, nous étudions les différentes approches permettant l’accès aux données dans les réseaux socionumériques, en nous intéressant − dans le cas précis de Facebook − à la qualité et la quantité de l’information accessible, et par conséquent, aux risques potentiels d’atteinte et de manipulation des données personnelles des utilisateurs par des tiers. Une expérimentation menée via l’API Facebook démontre l’accessibilité à un nombre important d’informations pouvant permettre de reconstruire automatiquement le réseau réel d’un utilisateur à partir de son profil.Social networks have been an object of analysis by the social sciences since the 1930s. The first challenge in performing these analyses is to gather information on the structure of these networks and on their activities. With the advent of Web 2.0 and semantic Web technologies, several different mechanisms can be used for this. However, few users are aware of how easy it is to access and manipulate the traces left by their activities and, especially on the social networks, by their personal data, which is becoming increasingly public. In this article, we look into the different ways of accessing data on the social networks, and – on Facebook in particular – into the quality and quantity of the information available and therefore the potential risks of users finding that third parties are accessing and manipulating their personal information. An experiment conducted via API Facebook shows that a great deal of information is accessible that can be used to automatically reconstruct a user’s actual network from their profile. (shrink)

The guest editors would like to thank the University of Paris and the ENSA Paris-Val de Seine for having provided premises to successfully host the 2018 "Measurement at the Crossroads" conference in Paris.Our thanks extend to our funding sources: the conference was made possible thanks to the generous support of the Institut Humanités, Sciences et Sociétés, the SPHERE laboratory and the Laboratoire Matériaux et Phénomènes Quantiques of the University of Paris, the department of History and Philosophy of Science of the (...) University of Paris, the Laboratoire National de métrologie et d'Essais, and the University of Geneva.We would like to thank the many people who contributed to the organization of... (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Bibliography of Resources by and about André E. Hellegers*Compiled by Doris Mueller Goldstein (bio)This bibliography is derived from the holdings of the National Reference Center for Bioethics Literature and the BIOETHICSLINE© database (both of which are at the Kennedy Institute of Ethics and supported by the National Library of Medicine); the archives of Lauinger Library, Georgetown University; the Medline databases of the National Library of Medicine; the WorldCat database (...) of OCLC, Dublin, Ohio, and selected Internet sites.Primarily comprised of writings by Dr. Hellegers, the list also includes interviews and media programs in which he participated, as well as writings about him that were written following his death. The arrangement within each section is by date. The 231 authored pieces reflect the transition from Dr. Hellegers’s early career as a researcher in fetal physiology at Johns Hopkins Medical School, where he published his first research report at the age of 29, to the early years of the Kennedy Institute, where he produced so many provocative columns on bioethical issues that influenced the growth of the field.Due to the diversity of sources and the 40-year time span covered, there are some variations in bibliographic style. Time and availability constraints precluded verifying all of the citations with the original documents. Any additions or corrections should be submitted to the compiler.Works Authored by André E. HellegersNo Date Ethical Issues in Sterilization of the Retarded. Unpublished paper.1956Vitamin B12 Serum Level and Pregnancy. American Journal of Clinical Nutrition 4: 440+, 1956. [With Bacon F. Chow and Kunio Okuda] [End Page 89]1957Vitamin B12 Absorption in Pregnancy and in the Newborn. American Journal of Clinical Nutrition 5: 327+, 1957. [With Bacon F. Chow, Robert E. L. Nesbitt, Kunio Okuda, and David W. Smith]1958The Effects of Acute Hypoxia on the Osmotic Pressure of the Plasma. Quarterly Journal of Experimental Physiology 43: 197+, 1958. [With Donald H. Barron, Frederick C. Battaglia, and Giacomo Meschia]Studies on the Absorption of Vitamin B12 in Human Pregnancy with Especial Reference to the Effect of D-Sorbitol. American Journal of Obstetrics and Gynecology 76: 91+, 1958. [With Bacon F. Chow, Harry Prystowsky, and Vernon Wong]1959The Alveolar PCO2 and PO2 in Pregnant and Nonpregnant Women at Altitude. Proceedings of the Society for Clinical Investigation 38: 1010+, 1959. [With Donald Barron, William Huckabee, Giacomo Meschia, James Metcalfe, and Harry Prystowsky]A Comparison of the Oxygen Dissociation Curves of the Bloods of Maternal and Fetal Goats at Various pHs. Quarterly Journal of Experimental Physiology 44: 215–21, July 1959. [With Donald Barron, Giacomo Meschia, Harry Prystowsky, and A. Stark Wolkoff]Fetal Blood Studies. XII. On the Relationship Between the Position of the Oxygen Dissociation Curve of Human Fetal Blood and Adult Fetal Hemoglobin. American Journal of Obstetrics and Gynecology 77: 585+, 1959. [With Paul D. Bruns, Julian Cotter, and Harry Prystowsky]Fetal Blood Studies. XIV. A Comparative Study of the Oxygen Dissociation Curve of Nonpregnant, Pregnant and Fetal Human Blood. American Journal of Obstetrics and Gynecology 78: 489–93, September 1959. [With Paul D. Bruns and Harry Prystowsky]Fetal Blood Studies. XVI. On the Changes in Total Osmotic Pressure and Sodium and Potassium Concentration of Amniotic Fluid During the Course of Human Gestation. Surgery, Gynecology and Obstetrics 109: 509–12, October 1959. [With Frederick Battaglia, Paul D. Bruns, Harry Prystowsky, and Clayton Smisson]Further Observations on the Metabolism of Vitamin B12 in Human Pregnancy. American Journal of Obstetrics and Gynecology 77: 1+, 1959. [With Bacon F. Chow, Harry Prystowsky, Bruno Ranke, and Elma Ranke]The Oxygen Dissociation Curves of the Bloods of Adult and Fetal Llamas. Federation Proceedings 18, 1959. [With Donald Barron, William Huckabee, Giacomo Meschia, James Metcalfe, and Harry Prystowsky] [End Page 90]Transfer of Oxygen Across the Sheep Placenta at High Altitude. Federation Proceedings 18, 1959. [With Donald Barron, William Huckabee, Giacomo Meschia, and Harry Prystowsky]Uterine Blood Flow and Metabolism in Pregnant Sheep at High Altitude. Federation Proceedings 18, 1959. [With Donald Barron, William Huckabee, Giacomo Meschia, James Metcalfe, and Harry Prystowsky]Uterine Blood Flow and Metabolism in Unanesthetized Pregnant Sheep. Federation Proceedings 18, 1959. [With Donald Barron, William Huckabee, Giacomo... (shrink)

Quelle(s) histoire(s) nous conte donc Marcela Iacub dans L’Empire du ventre? Celle, d’abord, non pas tant de « deux siècles d’établissement des liens de filiation » que des fondements juridiques et sociaux de ces liens. Liens que le Code civil de 1804 avait fait reposer sur l’institution du mariage et sur la volonté des parents, par l’entrée volontaire dans l’institution du mariage - synonyme de la volonté (ou de l’acceptation) de reconnaître a priori pour siens les enfants à naître dans (...) le... (shrink)

Le canon 812 du Code de droit canon de 1983 exige que ceux qui enseignent une discipline théologique dans une université catholique aient un mandatum de la part de l’autorité ecclésiastique compétente. Entre insistances et rappels à l’ordre romains, s’en suivirent aux Etats-Unis neuf ans de consultations, discussions et conflits qui impliquèrent évêques, présidents d’universités et théologiens. Il y a là un fait théologique et ecclésial dont les Eglises d’autres pays n’ont pas fait la même expérience. L’examen des enjeux ecclésiologiques (...) de ces péripéties constitue l’objet de ces réflexions qui représentent ainsi une sorte de lettre théologique des Etats-Unis. Pourquoi l’acuité de la question dans ce pays ? Comment comprendre le mandatum avec l’emploi du concept de communion ? Qu’est-ce que ce mandatum comme fait historique et comme institution ecclésiale ? Telles sont les questions auxquelles tente de répondre J.G. Mueller dans cet article.Canon 812 of the Code of Canon Law of 1983 requires that those who teach a theological discipline in a Catholic university have a mandatum from the competent church authority. In between Rome’s insistence and calls to order, there followed nine years of consultations, discussions, and conflicts in the United States involving bishops, university presidents, and theologians. This is a theological and ecclesial fact of which Churches in other countries have not had the same experience. An examination of the ecclesiological stakes of these vicissitudes constitutes the subject of these reflections, which represents a sort of theological letter from the United States. Why the acuity of the question in this country? How can we understand the mandatum by using the concept of communion? What is this mandatum as a historical fact and as an ecclesiastical institution? Such are the questions that J.G. Mueller attempts to answer in this article. (shrink)

© Ginn et al. 2016.The indexing methods currently used for serial femtosecond crystallography were originally developed for experiments in which crystals are rotated in the X-ray beam, providing significant three-dimensional information. On the other hand, shots from both X-ray free-electron lasers and serial synchrotron crystallography experiments are still images, in which the few three-dimensional data available arise only from the curvature of the Ewald sphere. Traditional synchrotron crystallography methods are thus less well suited to still image data processing. Here, a (...) new indexing method is presented with the aim of maximizing information use from a still image given the known unit-cell dimensions and space group. Efficacy for cubic, hexagonal and orthorhombic space groups is shown, and for those showing some evidence of diffraction the indexing rate ranged from 90% to 151%. Here, the indexing rate refers to the number of lattices indexed per image. (shrink)